Background
New Perspectives on Cerebellar Function: Implications for Mental Health. Society for Neuroscience 2019 Satellite Symposium.

New Perspectives on Cerebellar Function: Implications for Mental Health

The cerebellum has historically been associated with motor coordination, but our understanding of this structure is rapidly evolving. Research findings from the past two decades suggest that cerebellar circuits also play a broader role in cognitive, emotional, and social processes.

Cerebellar development and dysfunction have been linked to a variety of psychiatric disorders such ASD, ADHD, schizophrenia, and bipolar disorder.  Although the role of cerebellar circuits in psychiatric disorders is suggested by functional and structural imaging studies in humans, there have been relatively few studies that relate cerebellar dysfunction to specific symptoms in psychiatric disorders or provide a mechanistic understanding of the specific contributions of cerebellar circuits to cognitive function.

Recent technological advances in imaging, non-invasive brain stimulation, and molecular tools for animal models provide new opportunities to advance our understanding of non-motor cerebellar function and its role in mental health.

This workshop will bring together experts in basic and translational science to discuss the state of the field and identify opportunities to advance our understanding of how the cerebellum and its development contribute to cognition, emotion, and social behavior in both healthy and psychiatric populations.

Venue


Marriott Marquis Chicago
Meeting Room:  Great Lakes A
2121 South Prairie Avenue
Chicago, IL 60616 USA

Friday, October 18, 2019
8:30 AM – 5:00 PM CT

PLEASE NOTE: Lunch will be on your own. Visit the hotel website for on-site dining options.
Background

Speakers


Erik S. Carlson, M.D., Ph.D.
University of Washington
School of Medicine

Shruti Dave, Ph.D.
Northwestern University

John E. Desmond, Ph.D.
Johns Hopkins University
School of Medicine

Diasynou Fioravante, Ph.D.
University of California, Davis

Mark A. Halko, Ph.D.
Beth Israel Deaconess Medical Center

Detlef H. Heck, Ph.D.
University of Tennessee
Health Science Center

Alexandra L. Joyner, Ph.D.
Sloan Kettering Institute

Kamran Khodakhah, Ph.D.
Albert Einstein College of Medicine

Maedbh King
University of California, Berkeley

Krystal L. Parker, Ph.D.
University of Iowa

Jeremy D. Schmahmann, M.D.
Massachusetts General Hospital

Catherine Stoodley, DPhil.
American University

Peter T. Tsai, M.D., Ph.D.
University of Texas Southwestern
Medical Center

Samuel S. Wang, Ph.D.
Princeton University

Fay Y. Womer, M.D.
Washington University School of Medicine

Agenda


Society for Neuroscience 2019 Symposium
New Perspectives on Cerebellar Function:
Implications for Mental Health

8:30 A.M. – 8:45 P.M.

Introductions, Goals and Vision of the Meeting

Janine Simmons, M.D., Ph.D., Chief, Affective & Social Neuroscience Program, NIMH

Andrew Rossi Ph.D., Chief, Executive Functions and Reward Systems Program, NIMH

Joshua A. Gordon, M.D., Ph.D., Director, NIMH

8:45 A.M. – 10:45 A.M.

Basic Research in Animal Models

Krystal L. Parker, Ph.D. (University of Iowa), Cerebellar Circuits, Timing, and Cognition

Detlef H. Heck, Ph.D. (University of Tennessee), Coordination of cerebral-cortical coherence: a proposed neuronal mechanism of cerebellar cognitive function

Samuel S. Wang, Ph.D. (Princeton University), Cerebellar contribution to an evidence-accumulation decision-making task

Erik S. Carlson M.D., Ph.D. (University of Washington), Genetic dissection reveals different roles for intrinsic and extrinsic catecholaminergic innervation of the cognitive cerebellum

Diasynou Fioravante, Ph.D. (University of California, Davis), Cerebellar connections to the limbic system

Kamran Khodakhah, Ph.D. (Albert Einstein College of Medicine), Is the cerebellum a prediction machine for motivated behaviors?

10:45 A.M. – 11:00 A.M.

Coffee Break

11:00 A.M. – 11:20 P.M.

Questions & Panel Discussion

11:20 A.M. – 12:00 P.M.

Neurodevelopment

Alexandra Joyner, Ph.D. (Sloan Kettering Institute), Towards a molecular understanding of the excitatory cerebellar nuclei neurons

Peter Tsai M.D., Ph.D. (University of Texas Southwestern Medical Center), Cerebellar Contribution to Autism-related Behavior

12:00 P.M. – 12:15 P.M.

Questions & Panel Discussion

12:15 P.M. – 1:30 P.M.

Lunch on your own

1:30 P.M. – 2:45 P.M.

Basic Research in Humans

Maedbh King (University of California, Berkeley), Mapping the Human Cerebellum Using a Multi-Domain Task Battery

John Desmond, Ph.D. (Johns Hopkins University), Cerebellar Forward Model Contributions to Verbal Working Memory

Shruti Dave, Ph.D. (Northwestern University), Optimizing noninvasive modulation of executive-control and default-mode networks via cerebellar stimulation

Catherine Stoodley, Ph.D. (American University), Neural and behavioral effects of cerebellar tDCS on social learning

2:45 P.M. – 3:00 P.M.

Questions & Panel Discussion

3:00 P.M. – 3:15 P.M.

Coffee Break

3:15 P.M. – 4:15P.M.

Cerebellar Dysfunction and Psychiatric Disorders

Jeremy D. Schmahmann, M.D. (Harvard Medical School), Dysmetria of thought and the cerebellar cognitive affective syndrome: Anatomical principles and neuropsychiatry

Fay Womer, M.D. (Washington University School of Medicine), The cerebellar vermis and functional cerebral networks in schizophrenia, bipolar disorder, and major depressive disorder.

Mark Halko, Ph.D. (Harvard Medical School), Cognitive cerebellar-cortical network translational approaches for psychotic disorders

4:15 P.M. – 4:45 P.M.

Questions & Group Discussion

Gap Areas and Opportunities

Setting the Agenda for Future Research

4:45 P.M. – 5:00 P.M.

Meeting Adjourns

Registration


We have reached our maximum amount of registrations. To be added to the waitlist, please contact sbolling@thebizzellgroup.com
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Contact


If you have logistical questions, please contact:

Soncerray Bolling
Meeting Planner
The Bizzell Group
Email:  sbolling@thebizzellgroup.com

If you have programmatic questions, please contact:

Janine M. Simmons, M.D., Ph.D.
Chief, Affective and Social Neuroscience Program
National Institute of Mental Health
Email:  simmonsj@mail.nih.gov

Andrew Rossi, Ph.D.
Program Chief, Executive Functions and Reward Systems Program
National Institute of Mental Health
Email:  rossia@mail.nih.gov